All Publications

  • All Publications

Publications (all)

  1. J. Sapudom, T. Pompe. Biomimetic tumor microenvironments based on collagen matrices. Biomater Sci 6:2009-24 (2018). Link
  2. M. Ansorge, T. Pompe. Systems for localized release to mimic paracrine cell communication in vitro. J Control Release 278:24-36 (2018). Link
  3. L. Kalbitzer, and T. Pompe. Fibril growth kinetics link buffer conditions and topology of 3D collagen I networks. Acta Biomater 67:206-14 (2018). Link
  4. E. Muller, T. Pompe, U. Freudenberg, and C. Werner. Solvent-Assisted Micromolding of Biohybrid Hydrogels to Maintain Human Hematopoietic Stem and Progenitor Cells Ex Vivo. Adv Mater 29:1703489 (2017) Link
  5. J. Sapudom, J. Waschke, K. Franke, M. Hlawitschka, and T. Pompe. Quantitative label-free single cell tracking in 3D biomimetic matrices. Sci Rep 7:14135 (2017). Link
  6. M. Ansorge, J. Sapudom, M. Chkolnikov, M. Wilde, U. Anderegg, S. Moller, M. Schnabelrauch, and T. Pompe. Mimicking Paracrine TGFbeta1 Signals during Myofibroblast Differentiation in 3D Collagen Networks. Sci Rep 7:5664 (2017). Link
  7. J. Sapudom, X. Wu, M. Chkolnikov, M. Ansorge, U. Anderegg, and T. Pompe. Fibroblast fate regulation by time dependent TGF-beta1 and IL-10 stimulation in biomimetic 3D matrices. Biomater Sci 5:1858-67 (2017). Link
  8. M. Friedemann, L. Kalbitzer, S. Franz, S. Moeller, M. Schnabelrauch, J. C. Simon, T. Pompe and K. Franke. Instructing Human Macrophage Polarization by Stiffness and Glycosaminoglycan Functionalization in 3D Collagen Networks. Adv Healthc Mater  (2017). Link
  9. J. Sapudom, F. Ullm, S. Martin, L. Kalbitzer, J. Naab, S. Moller, M. Schnabelrauch, U. Anderegg, S. Schmidt, and T. Pompe. Molecular weight specific impact of soluble and immobilized hyaluronan on CD44 expressing melanoma cells in 3D collagen matrices. Acta Biomater 50:259-70 (2017). Link
  10. E. Muller, W. Wang, W. Qiao, M. Bornhauser, P. W. Zandstra, C. Werner, and T. Pompe. Distinguishing autocrine and paracrine signals in hematopoietic stem cell culture using a biofunctional microcavity platform. Sci Rep 6:31951 (2016). Link
  11. S. Martin, H. Wang, T. Rathke, U. Anderegg, S. Möller, M. Schnabelrauch, T. Pompe, and S. Schmidt. Polymer hydrogel particles as biocompatible AFM probes to study CD44/hyaluronic acid interactions on cells. Polymer 102:342-9 (2016). Link
  12. J. Sapudom, S. Rubner, S. Martin, and T. Pompe. Mimicking Tissue Boundaries by Sharp Multiparameter Matrix Interfaces. Adv Healthc Mater 5:1861-7 (2016). Link
  13. M. Ansorge, N. Rastig, R. Steinborn, T. Konig, L. Baumann, S. Moller, M. Schnabelrauch, M. Cross, C. Werner, A. G. Beck-Sickinger, and T. Pompe. Short-range cytokine gradients to mimic paracrine cell interactions in vitro. J Control Release 224:59-68 (2016). Link
  14. C. Müller, and T. Pompe. Distinct impacts of substrate elasticity and ligand affinity on traction force evolution. Soft Matter 12:272-80 (2016). Link
  15. L. Kalbitzer, F. Franke, S. Möller, M. Schnabelrauch, and T. Pompe. Glycosaminoglycan functionalization of mechanically and topologically defined collagen I matrices. J Materials Chemistry B 3:8902-10 (2015). Link
  16. J. Sapudom, S. Rubner, S. Martin, S. Thoenes, U. Anderegg, and T. Pompe. The interplay of fibronectin functionalization and TGF-beta1 presence on fibroblast proliferation, differentiation and migration in 3D matrices. Biomater Sci 3:1291-301 (2015). Link
  17. E. Müller, T. Grinenko, T. Pompe, C. Waskow, and C. Werner. Space constraints govern fate of hematopoietic stem and progenitor cells in vitro. Biomaterials 53:709-15 (2015). Link
  18. J. Sapudom, S. Rubner, S. Martin, T. Kurth, S. Riedel, C. T. Mierke, and T. Pompe. The phenotype of cancer cell invasion controlled by fibril diameter and pore size of 3D collagen networks. Biomaterials 52:367-75 (2015). Link
  19. S. Martin, H. Wang, L. Hartmann, T. Pompe, and S. Schmidt. Quantification of protein-materials interaction by soft colloidal probe spectroscopy. Physical chemistry chemical physics : PCCP 17:3014-18 (2015). Link
  20. E. Bach, T. Zerjatke, M. Herklotz, N. Scherf, D. Niederwieser, I. Roeder, T. Pompe, M. Cross, and I. Glauche. Elucidating functional heterogeneity in hematopoietic progenitor cells: A combined experimental and modeling approach. Exp Hematol 42:826-37 (2014). Link
  21. D. Pussak, D. Ponader, S. Mosca, T. Pompe, L. Hartmann, and S. Schmidt. Specific Adhesion of Carbohydrate Hydrogel Particles in Competition with Multivalent Inhibitors Evaluated by AFM. Langmuir 30:6142-50 (2014). Link
  22. K. Franke, J. Sapudom, L. Kalbitzer, U. Anderegg, and T. Pompe. Topologically defined composites of collagen types I and V as in vitro cell culture scaffolds. Acta Biomater 10:2693-702 (2014). Link
  23. A. Muller, J. Meyer, T. Paumer, and T. Pompe. Cytoskeletal transition in patterned cells correlates with interfacial energy model. Soft Matter 10:2444-52 (2014). Link
  24. C. Müller, A. Müller, and T. Pompe. Dissipative Interactions in Cell-Matrix Adhesion. Soft Matter 9:6207-16 (2013). Link
  25. T. Pompe, M. Prewitz, and C. Werner. Polymere Biomaterialien als zelluläre Mikromilieus. Biospektrum 20:383-84 (2012). 
  26. M. Prewitz, F. P. Seib, T. Pompe, and C. Werner. Polymeric Biomaterials for Stem Cell Bioengineering. Macromol Rapid Commun 33:1420-31 (2012). Link
  27. D. Stamov, and T. Pompe. Structure and function of ECM-based composite collagen I scaffolds. Soft Matter 8:10200-12 (2012). Link
  28. H. Perez-Hernandez, T. Paumer, T. Pompe, C. Werner, and A. F. Lasagni. Contactless laser-assisted patterning of surfaces for bio-adhesive microarrays. Biointerphases 7:35-43 (2012). Link
  29. N. Zhang, T. Pompe, I. Amin, R. Luxenhofer, C. Werner, and R. Jordan. Tailored Poly(2-oxazoline) Polymer Brushes to Control Protein Adsorption and Cell Adhesion. Macromol Biosci 12:926-36 (2012). Link
  30. C. Müller, D. Stamov, C. Werner, and T. Pompe. Nanoscale Characterization of Cell Receptors and Binding Sites on Cell-Derived Extracellular Matrices. Ultramicroscopy 118:44-52 (2012). Link
  31. J. Teichmann, A. Morgenstern, J. Seebach, H. J. Schnittler, C. Werner, and T. Pompe. The control of endothelial cell adhesion and migration by shear stress and matrix-substrate anchorage. Biomaterials 33:1959-69 (2012). Link
  32. N. Scherf, K. Franke, I. Glauche, I. Kurth, M. Bornhäuser, C. Werner, T. Pompe, and I. Roeder. On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup. Exp Hematol 40:119-30 (2012). Link
  33. I. Roeder, M. Loeffler, and I. Glauche. Towards a quantitative understanding of stem cell-niche interaction: experiments, models, and technologies. Blood Cells Mol Dis 46:308-17 (2011). Link
  34. D. R. Stamov, T. A. Khoa Nguyen, H. M. Evans, T. Pfohl, C. Werner, and T. Pompe. The impact of heparin intercalation at specific binding sites in telopeptide-free collagen type I fibrils. Biomaterials 32:7444-53 (2011). Link
  35. I. Kurth, K. Franke, T. Pompe, M. Bornhauser, and C. Werner. Extracellular matrix functionalized microcavities to control hematopoietic stem and progenitor cell fate. Macromol Biosci 11:739-47 (2011). Link
  36. M. Kaufmann, Y. Jia, C. Werner, and T. Pompe. Weakly coupled lipid bilayer membranes on multistimuli-responsive poly(N-isopropylacrylamide) copolymer cushions. Langmuir 27:513-6 (2011). Link
  37. T. Pompe, M. Kaufmann, M. Kasimir, S. Johne, S. Glorius, L. Renner, M. Bobeth, W. Pompe, and C. Werner. Friction controled traction forces in cell adhesion. Biophys J 101:1863-70 (2011). Link
  38. L. Renner, T. Pompe, R. Lemaitre, D. Drechsel, and C. Werner. Controlled enhancement of transmembrane enzyme activity in polymer cushioned supported bilayer membranes. Soft Matter 6:5382-89 (2010). Link
  39. T. Pompe, K. Salchert, K. Alberti, P. Zandstra, and C. Werner. Immobilization of growth factors on solid supports for the modulation of stem cell fate. Nat Protoc 5:1042-50 (2010). Link
  40. K. Lehmann, M. Herklotz, M. Espig, T. Paumer, M. Nitschke, C. Werner, and T. Pompe. A new approach to biofunctionalisation and micropatterning of multi-well plates. Biomaterials 31:8802-9 (2010). Link
  41. M. Kaufmann, Y. F. Jia, L. Renner, S. Gupta, D. Kuckling, C. Werner, and T. Pompe. Tuneable swelling of thermo- and pH-responsive copolymer films. Soft Matter 6:937-44 (2010). Link
  42. R. Grombe, M. F. Gouzy, U. Freudenberg, T. Pompe, S. Zschoche, F. Simon, K. J. Eichhorn, A. Janke, B. Voit, and C. Werner. Sulfated cellulose thin films with antithrombin affinity. Express Polym Lett 3:733-42 (2009). Link
  43. T. Pompe, S. Glorius, T. Bischoff, I. Uhlmann, M. Kaufmann, S. Brenner, and C. Werner. Dissecting the impact of matrix anchorage and elasticity in cell adhesion. Biophys J 97:2154-63 (2009). Link
  44. K. Franke, I. Kurth, M. Bornhäuser, C. Werner, and T. Pompe. Biomimetic Microcavities Based on Poly(dimethylsiloxane) Elastomers. Soft Matter 5:3505-10 (2009). Link
  45. D. Stamov, K. Salchert, A. Springer, C. Werner, and T. Pompe. Structural Polymorphism of Collagen Type I - Heparin Cofibrils. Soft Matter 5:3461-8 (2009). Link
  46. I. Kurth, K. Franke, T. Pompe, M. Bornhäuser, and C. Werner. Hematopoietic stem and progenitor cells in adhesive microcavities. Integr Biol 1:427-34 (2009). Link
  47. L. Renner, T. Pompe, and C. Werner. Electrostatic stretching of grafted maleic acid copolymer chains. Express Polym Lett 3:33-38 (2009). Link
  48. Z. Oezyuerek, K. Franke, M. Nitschke, R. Schulze, F. Simon, K. J. Eichhorn, T. Pompe, C. Werner, and B. Voit. Sulfated glyco-block copolymers with specific receptor and growth factor binding to support cell adhesion and proliferation. Biomaterials 30:1026-35 (2009). Link
  49. M. Herklotz, C. Werner, and T. Pompe. The impact of primary and secondary ligand coupling on extracellular matrix characteristics and formation of endothelial capillaries. Biomaterials 30:35-44 (2008). Link
  50. K. Alberti, R. E. Davey, K. Onishi, S. George, K. Salchert, F. P. Seib, M. Bornhauser, T. Pompe, A. Nagy, C. Werner, and P. W. Zandstra. Functional immobilization of signaling proteins enables control of stem cell fate. Nat Methods 5:645-50 (2008). Link
  51. L. Renner, T. Osaki, S. Chiantia, P. Schwille, T. Pompe, and C. Werner. Supported Lipid Bilayers on Spacious and pH-Responsive Polymer Cushions with Varied Hydrophilicity. J Phys Chem B 112:6373-78 (2008). Link
  52. D. Stamov, M. Grimmer, K. Salchert, T. Pompe, and C. Werner. Heparin intercalation into reconstituted collagen I fibrils: Impact on growth kinetics and morphology. Biomaterials 29:1-14 (2008). Link
  53. M. Herklotz, M. Melamed, C. Trautmann, M. Nitschke, T. Pompe, F. U. Gast, F. Howitz, and C. Werner. Non-contact printing of proteins on reactive polymer surfaces: a novel route towards structured and graded cell culture carriers. Microfluid Nanofluid 3:629-33 (2007). Link
  54. R. Grombe, M. F. Gouzy, M. F. Maitz, U. Freundenberg, S. Zschoche, F. Simon, T. Pompe, C. Sperling, and C. Werner. Sulfated glycopolymer thin films - preparation, characterization, and biological activity. Macromol Biosci 7:195-200 (2007). Link
  55. K. Franke, T. Pompe, M. Bornhauser, and C. Werner. Engineered matrix coatings to modulate the adhesion of CD133(+) human hematopoietic progenitor cells. Biomaterials 28:836-43 (2007). Link
  56. T. Pompe, K. Keller, G. Mothes, M. Nitschke, M. Teese, R. Zimmermann, and C. Werner. Surface modification of poly(hydroxybutyrate) films to control cell-matrix adhesion. Biomaterials 28:28-37 (2007). Link
  57. M. F. Gouzy, C. Sperling, K. Salchert, T. Pompe, C. Rauwolf, and C. Werner. Benzamidine-based coatings: Implication of inhibitor structure on the inhibition of coagulation enzymes in solution and in vitro hemocompatibility assessment. Biointerphases 1:146-55 (2006). Link
  58. T. Pompe, J. Starruss, M. Bobeth, and W. Pompe. Modeling of pattern development during fibronectin nanofibril formation. Biointerphases 1:93-97 (2006). Link
  59. T. Pompe, L. Renner, M. Grimmer, N. Herold, and C. Werner. Functional Films of Maleic Anhydride Copolymers under Physiological Conditions. Macromol Biosci 5:890-95 (2005). Link
  60. T. Pompe, K. Keller, C. Mitdank, and C. Werner. Fibronectin Fibril Pattern Displays the Force Balance of Cell-Matrix Adhesion  Eur Biophys J 34:1049-56 (2005). Link
  61. L. Renner, T. Pompe, K. Salchert, and C. Werner. Fibronectin Displacement at Polymer Surfaces. Langmuir 21:4571-77 (2005). Link
  62. T. Pompe, L. Renner, and C. Werner. Nanoscale Features of Fibronectin Fibrillogenesis Depend on Protein-Substrate Interaction and Cytoskeleton Structure. Biophys J 88:527-34 (2005). Link
  63. K. Salchert, U. Streller, T. Pompe, N. Herold, M. Grimmer, and C. Werner. In Vitro Reconstitution of Fibrillar Collagen Type I Assemblies at Reactive Polymer Surfaces. Biomacromolecules 5:1340-50 (2004). Link
  64. L. Renner, B. Jorgensen, M. Markowski, K. Salchert, C. Werner, and T. Pompe. Control o fibronectin displacement on polymer substrates to influence endothelial cell behaviour. J Mater Sci Mater Med 15:385-88 (2004). Link
  65. M. F. Gouzy, C. Sperling, K. Salchert, T. Pompe, U. Streller, P. Uhlmann, C. Rauwolf, F. Simon, F. Böhme, B. Voit, and C. Werner. In vitro blood compatibility of polymeric biomaterials through covalent immobilization of an amidine derivative. Biomaterials 25:3493-501 (2004). Link
  66. L. Renner, T. Pompe, K. Salchert, and C. Werner. Dynamic Alterations of Fibronectin Layers on Copolymer Substrates with Graded Physicochemical Characteristics. Langmuir 20:2928-33 (2004). Link
  67. T. Pompe, C. Mitdank, and C. Werner. Quantitative Analysis of Fibronectin Fibrillogenesis by Endothelial Cells on Biomaterials. J Phys: Cond Mat 16:S2421-S26 (2004). Link
  68. T. Pompe, M. Markowski, and C. Werner. Modulated Fibronectin Anchorage at Polymer Substrates Controls Angiogenesis. Tissue Eng 10:841-48 (2004). Link
  69. J. Oswald, B. Jorgensen, T. Pompe, F. Kobe, K. Salchert, M. Bornhauser, G. Ehninger, and C. Werner. Comparison of flow cytometry and laser scanning cytometry for the analysis of CD34+ hematopoietic stem cells. Cytometry 57A:100-07 (2004). Link
  70. K. Salchert, T. Pompe, C. Sperling, and C. Werner. Quantitative analysis of immobilized proteins and protein mixtures by amino acid analysis. J Chromatogr 1005:113-22 (2003). Link
  71. T. Pompe, F. Kobe, K. Salchert, B. Jorgensen, J. Oswald, and C. Werner. Fibronectin anchorage to polymer substrates controls the initial phase of endothelial cell adhesion. J Biomed Mater Res A 67:647-57 (2003). Link
  72. T. Pompe, S. Zschoche, N. Herold, K. Salchert, M. F. Gouzy, C. Sperling, and C. Werner. Maleic anhydride copolymers-a versatile platform for molecular biosurface engineering. Biomacromolecules 4:1072-79 (2003). Link
  73. T. Pompe. Line tension behavior of a first-order wetting system. Phys Rev Lett 89:076102 (2002). Link
  74. S. Herminghaus, T. Pompe, and A. Fery. Scanning Force Investigation of Liquid Structures and its Application to Fundamental Wetting Research. J Adh Sci Technol 14:1767-82 (2000). Link
  75. T. Pompe, and S. Herminghaus. Three-phase contact line energetics from nanoscale liquid surface topographies. Phys Rev Lett 85:1930-33 (2000). Link
  76. S. Herminghaus, A. Fery, S. Schlagowski, K. Jacobs, R. Seemann, H. Gau, W. Mönch, and T. Pompe. Liquid microstructures at solid interfaces. J Phys: Cond Mat 12:A57-A74 (2000). Link
  77. T. Pompe, A. Fery, and S. Herminghaus. Measurement of Contact Line Tension by Analysis of the Three-Phase Boundary with Nanometer Resolution. J Adhesion Sci Technol 13:1155-64 (1999). Link
  78. A. Fery, T. Pompe, and S. Herminghaus. Nanometer Resolution of Liquid Surface Topography by Scanning Force Microscopy. J Adhesion Sci Technol 13:1071-83 (1999). Link
  79. T. Pompe, A. Fery, A. Kriele, H. Lorenz, and J. P. Kotthaus. Submicron Contact Printing on Silicon Using Stamp Pads. Langmuir 15:2398-401 (1999). Link
  80. T. Pompe, S. Herminghaus, and A. Fery. Imaging Liquid Structures on Inhomogeneous Substrates by Scanning Force Microscopy. Langmuir 14:2585-88 (1998). Link
  81. T. Pompe, V. Srikant, and D. R. Clarke. Acoustoelectric current saturation in c-axis fiber-textured polycrystalline zinc oxide films. Appl Phys Lett 69:4065-67 (1996). Link
letzte Änderung: 09.08.2018

Kontakt

Prof. Dr. Tilo Pompe
Universität Leipzig
Institute of Biochemistry
Johannisallee 21-23
04103 Leipzig

Telefon: +49 341 97-36931
Telefax: +49 341 97-36939
E-Mail

Sekretariat
Petra Zamzow
Raum 1.34

Telefon: +49 341 97-36930
Telefax: +49 341 97-36939
E-Mail

News

New Paper on Surface Functionalization of Polyarcylamide Hydrogels

10.08.2018

We published a new paper in Macromolecular Chemistry and Physics. In this study we reveal the mechanism, how surfaces of soft polyacrylamide hydrogel...

New Review Paper on Biomimetic Tumor Microenvironments

12.07.2018

In a new paper Jiranuwat Sapudom reviews the current state-of-the-art article on engineering biomimetic 3D tumor microenvironments for in vitro...

New Review Paper on Local Cytokine Release Systems

10.04.2018

Based on the expertise gathered throughout his PhD work Michael Ansorge published a review article on local cytokine release systems to mimic...